SPECIALIST SIGNAL PROFILERS FOR BASE CALLING

We disclose a system. The system comprises a memory and a runtime logic. The memory stores a plurality of specialist signal profilers. Each specialist signal profiler in the plurality of specialist signal profilers is trained to maximize signal-to-noise ratio of sequenced signals in a particular sig...

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Bibliographic Details
Main Authors OJARD, Eric Jon, PARNABY, Gavin Derek, UDPA, Nitin, VIECELI, John S, MEHIO, Rami, KAGALWALLA, Abde Ali Hunaid
Format Patent
LanguageEnglish
French
German
Published 29.05.2024
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Summary:We disclose a system. The system comprises a memory and a runtime logic. The memory stores a plurality of specialist signal profilers. Each specialist signal profiler in the plurality of specialist signal profilers is trained to maximize signal-to-noise ratio of sequenced signals in a particular signal profile detected for analytes in a particular analyte class and characterized in a particular training data set. The runtime logic, having access to the memory, is configured to execute a base calling operation by applying respective specialist signal profilers in the plurality of specialist signal profilers to sequenced signals in respective signal profiles detected for analytes in respective analyte classes during the base calling operation.
Bibliography:Application Number: EP20220751936