AFFINITY LIGANDS FOR THE PURIFICATION AND DETECTION OF UBIQUITIN MUTEINS
The present invention relates to novel affinity ligands for the affinity purification of ubiquitin muteins. In particular, the alkaline stable affinity ligands are useful for affinity chromatography purification and detection of a ubiquitin mutein (such as Affilin® protein). The novel affinity ligan...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English French German |
| Published |
22.05.2024
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to novel affinity ligands for the affinity purification of ubiquitin muteins. In particular, the alkaline stable affinity ligands are useful for affinity chromatography purification and detection of a ubiquitin mutein (such as Affilin® protein). The novel affinity ligands for a ubiquitin mutein are based on artificial mosaic proteins of Protein A-like structure. The affinity ligands of the invention can be used for the purification and detection of ubiquitin muteins. |
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| AbstractList | The present invention relates to novel affinity ligands for the affinity purification of ubiquitin muteins. In particular, the alkaline stable affinity ligands are useful for affinity chromatography purification and detection of a ubiquitin mutein (such as Affilin® protein). The novel affinity ligands for a ubiquitin mutein are based on artificial mosaic proteins of Protein A-like structure. The affinity ligands of the invention can be used for the purification and detection of ubiquitin muteins. |
| Author | SETTELE, Florian FIEDLER, Erik KATZSCHMANN, Anja KAHL, Mathias |
| Author_xml | – fullname: KAHL, Mathias – fullname: SETTELE, Florian – fullname: KATZSCHMANN, Anja – fullname: FIEDLER, Erik |
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| DocumentTitleAlternate | AFFINITÄTSLIGANDEN ZUR REINIGUNG UND DETEKTION VON UBIQUITINMUTEINEN LIGANDS D'AFFINITÉ POUR LA PURIFICATION ET LA DÉTECTION DE MUTÉINES D'UBIQUITINE |
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| Notes | Application Number: EP20220741483 |
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| Snippet | The present invention relates to novel affinity ligands for the affinity purification of ubiquitin muteins. In particular, the alkaline stable affinity ligands... |
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| Title | AFFINITY LIGANDS FOR THE PURIFICATION AND DETECTION OF UBIQUITIN MUTEINS |
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