AFFINITY LIGANDS FOR THE PURIFICATION AND DETECTION OF UBIQUITIN MUTEINS

The present invention relates to novel affinity ligands for the affinity purification of ubiquitin muteins. In particular, the alkaline stable affinity ligands are useful for affinity chromatography purification and detection of a ubiquitin mutein (such as Affilin® protein). The novel affinity ligan...

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Bibliographic Details
Main Authors KAHL, Mathias, SETTELE, Florian, KATZSCHMANN, Anja, FIEDLER, Erik
Format Patent
LanguageEnglish
French
German
Published 22.05.2024
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates to novel affinity ligands for the affinity purification of ubiquitin muteins. In particular, the alkaline stable affinity ligands are useful for affinity chromatography purification and detection of a ubiquitin mutein (such as Affilin® protein). The novel affinity ligands for a ubiquitin mutein are based on artificial mosaic proteins of Protein A-like structure. The affinity ligands of the invention can be used for the purification and detection of ubiquitin muteins.
Bibliography:Application Number: EP20220741483