ADMINISTRATION OF NAKED NUCLEIC ACID MOLECULE

Provided herein is a method of administering a naked nucleic acid molecule to a subject. The method may include injecting the naked nucleic acid molecule to the subject, wherein the injecting exhibits a bi-phasic injection profile comprising a first phase and a second phase, the second phase being a...

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Bibliographic Details
Main Authors YAMASHITA, Kunihiko, SAKAGUCHI, Naoki, TERAI, Kazuhiro
Format Patent
LanguageEnglish
French
German
Published 15.05.2024
Subjects
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMISTRY
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Summary:Provided herein is a method of administering a naked nucleic acid molecule to a subject. The method may include injecting the naked nucleic acid molecule to the subject, wherein the injecting exhibits a bi-phasic injection profile comprising a first phase and a second phase, the second phase being after the first phase, and the bi-phasic injection profile has (i) at least two peaks within 15 msec from the injecting, (ii) the first peak of at least 2 MPa, or (iii) the highest peak of the second phase of the bi-phasic injection within 30 msec from the injecting.
Bibliography:Application Number: EP20220744832