METHOD OF MAKING A LOW-SILICONE OIL SYSTEM FOR A MEDICAL INJECTION DEVICE

• Main Authors: JOUFFRAY, Sébastien, DELEUIL, Nicolas, PERRIN, Eloïse, RODRIGUEZ SAN JUAN, Nestor, LEHEE, Guillaume
• Format: Patent
• Language: English; French; German
• Published: 10.04.2024
• Subjects: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE

A method for storing an article within a pre-filled silicone-free barrel for use as a medical injection device, the barrel comprising a tubular member having inner and outer surfaces, the article comprising an elastomeric material having at least a partial coating of a fluoropolymer material on at least a front face thereof. wherein the article has between two and four perimetrical contact surfaces with respect to the inner surface of the barrel, the perimetrical contact surfaces separately disposed with respect to each other along a longitudinal length of the article and the barrel, wherein the method of storing the article within the pre-filled silicone-free barrel comprises storing the article within the pre-filled silicone-free barrel in cold storage at temperatures within the range of −80° C. to −40° C. and wherein the container closure integrity (CCI) of the article within the pre-filled silicone-free barrel is maintained upon thawing to ambient conditions.