SUBSTITUTED SPIRO DERIVATIVES

The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MD...

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Bibliographic Details
Main Authors COLOMBEL, Hélène France Solange, DAI, Xuedong, KRAMER, Carsten Sven, FANG, Lichao, XU, Yanping, PILATTE, Isabelle Noëlle Constance, PONCELET, Virginie Sophie, LIU, Yingtao, PANDE, Vineet, CAI, Wei, QUEROLLE, Olivier Alexis Georges, THURING, Johannes Wilhelmus J, QIN, Luoheng, WU, Jianping, ANGIBAUD, Patrick René, LIU, Lianzhu, LI, Ming
Format Patent
LanguageEnglish
French
German
Published 13.03.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MDS) and diabetes.
Bibliography:Application Number: EP20220725155