PRODUCTION OF CRM197

The invention relates to a method for producing a protein in a Corynebacterium cell, wherein the protein is a non-toxic variant of diphtheria toxin and wherein a signal peptide having at least 90% sequence identity to SEQ ID NO: 1 or SEQ ID NO: 5 is fused to the protein.

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Bibliographic Details
Main Author SCHAUMANN, Georg
Format Patent
LanguageEnglish
French
German
Published 21.02.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to a method for producing a protein in a Corynebacterium cell, wherein the protein is a non-toxic variant of diphtheria toxin and wherein a signal peptide having at least 90% sequence identity to SEQ ID NO: 1 or SEQ ID NO: 5 is fused to the protein.
Bibliography:Application Number: EP20220191096