SUBSTITUTED PYRIDINES AS DNMT1 INHIBITORS
The invention relates to substituted pyridine derivatives that are inhibitors of the activity of DNA methyltransferase 1 (DNMT1). The invention also relates to pharmaceutical compositions comprising such compounds and methods of using such compounds in the treatment of cancer, pre-cancerous syndrome...
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Main Authors | , , , |
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Format | Patent |
Language | English French German |
Published |
10.01.2024
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Subjects | |
Online Access | Get full text |
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Summary: | The invention relates to substituted pyridine derivatives that are inhibitors of the activity of DNA methyltransferase 1 (DNMT1). The invention also relates to pharmaceutical compositions comprising such compounds and methods of using such compounds in the treatment of cancer, pre-cancerous syndromes, beta haemoglobinopathy disorders, and other diseases associated with inappropriate DNMT1 activity. |
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Bibliography: | Application Number: EP20220707881 |