REGULATORY T CELL (TREG) EXTRACELLULAR VESICLE COMPOSITIONS AND METHODS

The present disclosure provides anti-inflammatory extracellular vesicles (EVs) derived from ex vivo-expanded human suppressive immune cells. e.g., regulatory T cells (Tregs). Such EVs are useful in the treatment of diseases such as amyotrophic lateral sclerosis (AES). Alzheimer's disease, and o...

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Bibliographic Details
Main Authors THONHOFF, Jason, Robert, THOME, Aaron, Drew, APPEL, Stanley, Hersh
Format Patent
LanguageEnglish
French
German
Published 03.01.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The present disclosure provides anti-inflammatory extracellular vesicles (EVs) derived from ex vivo-expanded human suppressive immune cells. e.g., regulatory T cells (Tregs). Such EVs are useful in the treatment of diseases such as amyotrophic lateral sclerosis (AES). Alzheimer's disease, and other neurological diseases, as well as inflammatory and autoimmune diseases or dysfunctions.
Bibliography:Application Number: EP20220760524