AN OLIGOMERIZATION TAG COMPRISING AN IMMUNOGLOBULIN FC REGION AND A POLYHIS DOMAIN

A composition that binds to an anti-CD38 antibody includes a specific sequence of a recombinant soluble form of an extracellular domain of CD38 and/or a fragment thereof that interferes with binding activity of the anti-CD38 antibody. The composition can be included in a kit for bio-monitoring resea...

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Bibliographic Details
Main Authors BOOTH, ELIZABETH A, FAVALORO, VINCENZO, BERRY, JODY, BINDA, MATTEO, HALL, JOHN A, SCHWIND, PETER
Format Patent
LanguageEnglish
French
German
Published 27.12.2023
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:A composition that binds to an anti-CD38 antibody includes a specific sequence of a recombinant soluble form of an extracellular domain of CD38 and/or a fragment thereof that interferes with binding activity of the anti-CD38 antibody. The composition can be included in a kit for bio-monitoring research and diagnostic assays. The composition can be used to neutralize an anti-CD38 antibody in a sample and/or to select a suitable red blood cell unit for a patient treated with anti-CD38 antibodies.
Bibliography:Application Number: EP20230205907