ANTI-LESION STORAGE METHOD AND STORAGE SYSTEM FOR CELLS, TISSUES OR ORGANS

• Main Authors: HU, Yifan, HUANG, Peigeng
• Format: Patent
• Language: English; French; German
• Published: 18.10.2023
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; TRAPPING

The disclosure discloses an anti-lesion storage method and storage system for cells, tissues and organs, and relates to the technical field of storage of cells, tissues or organs. The method includes: adjusting a partial pressure of carbon dioxide in a suspension medium containing the cells, tissues or organs to be stored to 30-50 mmHg. The regulation of the partial pressure of carbon dioxide in the suspension medium is advantageous for improving anti-lesions, and in particular can prolong the in vivo survival of platelets after transfusion and protect the hemostatic function of platelets whiling effectively alleviating platelet storage lesions. The method may comprise filling an air-tight container with a gas mixture, or placing the platelet concentrate into a gas permeable container within a three-gas storage apparatus, or into a container equipped with a one-way gas valve or made out of a one-way gas permeable material, wherein further a substance capable of producing carbon dioxide by a chemical reaction may be added.