METHODS FOR DECREASING MORTALITY RISK AND IMPROVING HEALTH

The disclosure provides methods for decreasing mortality risk and/or improving health in a subject. In some aspects, the disclosure provides methods of using one or more biomarkers to determine the risk of mortality, detect an increase or decrease over time in the risk of mortality, or detect an imp...

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Bibliographic Details
Main Authors STEFÁNSSON, Kari, EIRIKSDOTTIR, Thjodbjorg, ÚLFARSSON, Magnús, GUDBJARTSSON, Daniel
Format Patent
LanguageEnglish
French
German
Published 20.09.2023
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Summary:The disclosure provides methods for decreasing mortality risk and/or improving health in a subject. In some aspects, the disclosure provides methods of using one or more biomarkers to determine the risk of mortality, detect an increase or decrease over time in the risk of mortality, or detect an improvement or decline in health of a subject that occurs, for example, over time, in response to therapeutic intervention, or as a result of changes in diet, fitness, or other lifestyle changes. In some other aspects, the disclosure provides methods for treating a subject to reduce the mortality risk of the subject. Additionally, the disclosure provides methods for using changes in the risk of mortality of a subject to monitor the effectiveness of a therapeutic treatment, dietary restrictions, fitness regimen, or other intervention in a subject, and for continuing, discontinuing, or altering the treatment, restrictions, regimen, or intervention accordingly. Further, the disclosure provides methods for predicting effectiveness of a therapeutic treatment in a subject determined to be at an increased risk of mortality and subsequently treating the subject with the therapeutic treatment if the biomarker level is indicative of effectiveness of the treatment of the subject.
Bibliography:Application Number: EP20210815843