METHOD FOR HYDRODYNAMICS-ASSISTED MULTI-PARAMETER ANALYTE SPECTROMETRY

• Main Authors: MARTÍN PÉREZ, Alberto, CALLEJA GÓMEZ, Montserrat, RAMOS VEGA, Daniel, TAMAYO DE MIGUEL, Francisco Javier
• Format: Patent
• Language: English; French; German
• Published: 13.09.2023
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The method uses a suspended resonating microcapillary device, and obtains simultaneously three parameters of the analytes: mass, size and refractive index, enabling the unequivocal classification of the analytes flowing in real time, based on the resonance frequency displacement and the change in reflectivity of the transparent microcapillary. The method comprises the stages of: the obtaining of a measurement of the reflectivity of the sample analytes within the capillary at each moment in time; the obtaining of a mechanical reference signal (Tt) of the change in resonance frequency of the microcapillary caused by the sample analytes over time; and the detection of the passage of the particle through an area of the capillary, and the obtaining of the points of passage of the ends of the analytes through the centre of the illuminated area, obtaining an optical signal ΔT.