PYRAZOLE DERIVATIVES AS RET KINASE INHIBITORS

Disclosed herein are compounds of formula I:or a pharmaceutically acceptable salt thereof, where the variables are as defined herein. These compounds are useful in treating RET associated cancers. Formulations containing the compounds of formula I and methods of making the compounds of formula I are...

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Bibliographic Details
Main Authors MCFADDIN, Elizabeth, A, ANDREWS, Steven, W, ANDERSON, Erin, D, PILKINGTON-MIKAS, Michael, Alexander, MCKENNEY, Megan, L, MCLEAN, Johnathan, Alexander, MUNCHHOF, Michael, J, PANCALDI, Thomas, Pierre, Dino, KUMAR, Manoj, CONDROSKI, Kevin, R, BOLDRON, Christopher, Pierre, Albert, Jean, PINTO, Marta, IRVIN, Thomas, C, KOLAKOWSKI, Gabrielle,R, MOURET, Tiphaine
Format Patent
LanguageEnglish
French
German
Published 13.09.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed herein are compounds of formula I:or a pharmaceutically acceptable salt thereof, where the variables are as defined herein. These compounds are useful in treating RET associated cancers. Formulations containing the compounds of formula I and methods of making the compounds of formula I are also disclosed.
Bibliography:Application Number: EP20210815830