TWO-DOMAIN MULTIMERIC FUSION PROTEINS

Provided are conjugates of TRAIL and another Tumor Necrosis Factor (TNF) superfamily ligand, and related compositions and methods of use thereof. Also provided are conjugates of two trimeric polypeptides linked through a genetically encoded linker or chemical linkers and related compositions and met...

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Bibliographic Details
Main Author BRIN, Elena
Format Patent
LanguageEnglish
French
German
Published 06.09.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided are conjugates of TRAIL and another Tumor Necrosis Factor (TNF) superfamily ligand, and related compositions and methods of use thereof. Also provided are conjugates of two trimeric polypeptides linked through a genetically encoded linker or chemical linkers and related compositions and methods of use thereof.
Bibliography:Application Number: EP20210887783