PROCESS FOR THE PRODUCTION OF CANNABINOL, CANNABINOLIC ACID, CANNABIVARIN, CANNABIVARINIC ACID AND RELATED CANNABINOIDS

A process for the preparation of diverse known and novel cannabinoids (5), which include cannabinol (CBN, 1), cannabinolic acid (CBNA, 2), cannabivarin (CBV, 3) and cannabivarinic acid (CBVA, 4) and other naturally occurring monocyclic and tricyclic cannabinoids and other analogues from simple inexp...

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Bibliographic Details
Main Authors PARSONS, Philip, J, ELLIOTT, Daniel, BERKOWITZ, Barry, A, BARRETT, Anthony, G
Format Patent
LanguageEnglish
French
German
Published 09.08.2023
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:A process for the preparation of diverse known and novel cannabinoids (5), which include cannabinol (CBN, 1), cannabinolic acid (CBNA, 2), cannabivarin (CBV, 3) and cannabivarinic acid (CBVA, 4) and other naturally occurring monocyclic and tricyclic cannabinoids and other analogues from simple inexpensive starting materials using a cascade sequence of allylic rearrangement, aromatization and, as appropriate, further highly selective cyclization reactions. Additionally, cannabinoids of the formula (5) and intermediates of the formula (9) form part of the invention. Use of medicaments comprising one or more of the disclosed cannabinoids alone or admixed with one or more other cannabinoids is also disclosed.
Bibliography:Application Number: EP20210876462