ORGANOID RECOMBINATION

Disclosed herein are organoid compositions having heterogeneous combinations of epithelial and mesenchymal components, and methods of making the same by dissociating and recombining the epithelial and mesenchymal components from different sources. These epithelial and mesenchymal components can be d...

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Bibliographic Details
Main Authors BROWN, Nicole, SINGH, Akaljot, SUNDARAM, Nambirajan, VALES, Simon, HELMRATH, Michael, A
Format Patent
LanguageEnglish
French
German
Published 09.08.2023
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Summary:Disclosed herein are organoid compositions having heterogeneous combinations of epithelial and mesenchymal components, and methods of making the same by dissociating and recombining the epithelial and mesenchymal components from different sources. These epithelial and mesenchymal components can be derived from the same or different cell type or organoid type. These organoid compositions may exhibit advantageous properties, for example, enhanced in vivo engraftment.
Bibliography:Application Number: EP20210876429