ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS

The present disclosure provides scaffolds and antibody-drug conjugates (ADCs) comprising a stimulator of interferon genes (STING). The present disclosure also provides uses of the ADCs in treatment, e.g., treatment of cancer.

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Bibliographic Details
Main Authors KELLEHER, Eugene W, DAMELIN, Marc I, XU, Ling, THOMAS, Joshua D, BENTLEY, Keith W, DUVALL, Jeremy R, TOADER, Dorin, BUKHALID, Raghida A, CETINBAS, Naniye, LOWINGER, Timothy B, YANG, Liping
Format Patent
LanguageEnglish
French
German
Published 02.08.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure provides scaffolds and antibody-drug conjugates (ADCs) comprising a stimulator of interferon genes (STING). The present disclosure also provides uses of the ADCs in treatment, e.g., treatment of cancer.
Bibliography:Application Number: EP20220215179