POLYPEPTIDE AND METHOD FOR PRODUCING AMINO ACID USING SAME

The polypeptide comprises a sequence having 90% or higher sequence identity to an amino acid sequence represented by SEQ ID NO: 1 with one amino acid residue thereof engineered, and has higher catalytic activity for the reductive amination reaction between at least one compound A represented by the...

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Main Authors OHTA, Atsushi, NAKANO, Kazuhiko, ISHINO, Sou, MATSUO, Atsushi, TSUKADA, Keisuke, ISHIYAMA, Shiori, SHIINA, Junichi, SHINODA, Kiyomichi, EJIMA, Hirotaka
Format Patent
LanguageEnglish
French
German
Published 06.09.2023
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The polypeptide comprises a sequence having 90% or higher sequence identity to an amino acid sequence represented by SEQ ID NO: 1 with one amino acid residue thereof engineered, and has higher catalytic activity for the reductive amination reaction between at least one compound A represented by the formula (1) or a salt thereof and at least one compound B represented by the formula (2) or a salt thereof or the intramolecular reductive amination reaction of at least one compound B or a salt thereof than that of a polypeptide comprising the amino acid sequence represented by SEQ ID NO: 1 under at least one reaction condition.
Bibliography:Application Number: EP20220216504