PREFERENTIAL GENERATION OF IPSC CARRYING ANTIGEN SPECIFIC TCRS FROM TUMOR INFILTRATING LYMPHOCYTES

Disclosed are methods for reprogramming cancer-reactive T cells into iPSC cells as well as methods utilizing such cells for the identification of cancer-antigen specific TCRs and the treatment of cancer.

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Bibliographic Details
Main Authors ISLAM, SM Rafiqul, RESTIFO, Nicholas P, VIZCARDO, Raul E, MAEDA, Takuya, TAMAOKI, Naritaka
Format Patent
LanguageEnglish
French
German
Published 28.06.2023
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Disclosed are methods for reprogramming cancer-reactive T cells into iPSC cells as well as methods utilizing such cells for the identification of cancer-antigen specific TCRs and the treatment of cancer.
Bibliography:Application Number: EP20210769306