ENRICHMENT OF T CELLS USING AN ANTI-CBETA ANTIBODY

The present invention describes methods and uses of antibodies targeting the Cβ1 or the Cβ2 chain of a TCR, in particular an anti-Cβ1 antibody, for enrichment of T cells expressing a desired antigen-specific recombinant T cell receptor (TCR).

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Bibliographic Details
Main Authors SOMMERMEYER, Daniel, MILOSEVIC, Slavoljub, SCHLEICHER, Anna
Format Patent
LanguageEnglish
French
German
Published 24.07.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention describes methods and uses of antibodies targeting the Cβ1 or the Cβ2 chain of a TCR, in particular an anti-Cβ1 antibody, for enrichment of T cells expressing a desired antigen-specific recombinant T cell receptor (TCR).
Bibliography:Application Number: EP20210765616