MICROFLUIDIC DEVICES AND METHODS FOR DELIVERING SOLUTIONS TO BIOLOGICAL MATERIAL

Disclosed herein are microfluidic devices and methods to deliver concentration gradients to biological material such as oocytes and embryos for the purpose of cryopreparation, cryopreservation, or thawing. Cryopreservation methods, such as vitrification, involve the use of cryoprotectants to reduce...

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Main Authors HORCAJADAS ALMANSA, José Antonio, DOSDA MUNUERA, Cristina, MATTHYS, Lionel, SALES FIDALGO, Joana Alexandra, MUNNE, Santiago, CARASA RUIZ, Pablo, ALVAREZ ARGUELLES, Sara, CANCIO VILLALONGA, David, GARCIA ALONSO, Daniel
Format Patent
LanguageEnglish
French
German
Published 14.06.2023
Subjects
DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
MEDICAL OR VETERINARY SCIENCE
SURGERY
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Summary:Disclosed herein are microfluidic devices and methods to deliver concentration gradients to biological material such as oocytes and embryos for the purpose of cryopreparation, cryopreservation, or thawing. Cryopreservation methods, such as vitrification, involve the use of cryoprotectants to reduce formation of damaging ice crystals in cells during freezing. Microfluidic devices and methods described herein improve cell viability and efficiency during handling and cryopreservation of biological materials.
Bibliography:Application Number: EP20210854025