CYCLIZED ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS
The present invention relates to methods for treating bacterial infections caused by orProvided and set forth herein are certain cyclized acetamido derivatives that are DNA Polymerase Theta (Polθ) inhibitors of Formula (I) and Formula II.Also, provided are pharmaceutical compositions comprising such...
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Main Authors | , , , |
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Format | Patent |
Language | English French German |
Published |
07.06.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to methods for treating bacterial infections caused by orProvided and set forth herein are certain cyclized acetamido derivatives that are DNA Polymerase Theta (Polθ) inhibitors of Formula (I) and Formula II.Also, provided are pharmaceutical compositions comprising such compounds, and methods of treating diseases treatable by inhibition of Polθ such as cancer, including homologous recombination (HR) deficient cancers, using such compounds and pharmaceutical compositions. |
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Bibliography: | Application Number: EP20210756144 |