NOVEL PLK1 DEGRADATION INDUCING COMPOUND

The present disclosure relates to a novel PLK1 degradation inducing compound having a structure according to Formula I, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the presen...

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Bibliographic Details
Main Authors KIM, Sang Youn, RYU, Hye Guk, RYU, Soo Hee, MIN, Im Suk, LEE, Han Kyu, KIM, Seong Hoon, KANG, Keum Young, CHUNG, So Hyun, LEE, Jun Kyu, LEE, Gibbeum
Format Patent
LanguageEnglish
French
German
Published 05.04.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure relates to a novel PLK1 degradation inducing compound having a structure according to Formula I, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.
Bibliography:Application Number: EP20220808930