DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC

Methods are provided that relate to the discovery that dihomo-gamma linolenic acid (DGLA) is a potent senolytic agent. Accordingly, in certain embodiments, methods of selectively killing one or more senescent cells in a subject in need thereof are provided wherein the method(s) involves administerin...

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Bibliographic Details
Main Authors WILEY, Christopher D, CAMPISI, Judith
Format Patent
LanguageEnglish
French
German
Published 05.04.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Methods are provided that relate to the discovery that dihomo-gamma linolenic acid (DGLA) is a potent senolytic agent. Accordingly, in certain embodiments, methods of selectively killing one or more senescent cells in a subject in need thereof are provided wherein the method(s) involves administering to the subject an effective amount of DGLA.
Bibliography:Application Number: EP20210816897