SAFE USE OF BILE ACIDS AND THEIR SALTS AS ENHANCERS FOR NASAL DELIVERY OF PHARMACEUTICALS
The present disclosure introduces safe and effective pharmaceutical formulations for intranasal delivery. Specifically, the present disclosure introduces the safe clinical use of bile acids or salts thereof as an enhancer to exhibit improved bioavailability and tissue tolerance. In several embodimen...
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Main Authors | , , , |
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Format | Patent |
Language | English French German |
Published |
15.03.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The present disclosure introduces safe and effective pharmaceutical formulations for intranasal delivery. Specifically, the present disclosure introduces the safe clinical use of bile acids or salts thereof as an enhancer to exhibit improved bioavailability and tissue tolerance. In several embodiments, pharmaceutical formulations including bile acids or salts thereof are provided. In several embodiments, the formulations are suitable and/or configured for the intranasal (IN) delivery, methods of manufacturing such formulations, and methods of treating patients using such formulations. The pharmaceutical formulations comprising bile acids, salts of bile acids, and/or combinations thereof. In several embodiments, bile acids, salts of bile acids, and/or combinations thereof are configured for use as absorption enhancers. |
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Bibliography: | Application Number: EP20210799494 |