EPINEPHRINE PHARMACEUTICAL FORMULATIONS FOR INTRANASAL DELIVERY

The present disclosure introduces pharmaceutical formulations having epinephrine as the active pharmaceutical ingredient (API), and a bile acid, or salt thereof (e.g., sodium taurocholate (STC)) as an absorption enhancer, for intranasal (IN) delivery. The bile acid, or the salt thereof, enhances abs...

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Bibliographic Details
Main Authors BO, Aili, LUO, Mary, Zi-ping, ZHANG, Jack, Yongfeng, DING, Jie Fei
Format Patent
LanguageEnglish
French
German
Published 15.03.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present disclosure introduces pharmaceutical formulations having epinephrine as the active pharmaceutical ingredient (API), and a bile acid, or salt thereof (e.g., sodium taurocholate (STC)) as an absorption enhancer, for intranasal (IN) delivery. The bile acid, or the salt thereof, enhances absorption of epinephrine by IN delivery. Also disclosed are methods of administering epinephrine to a patient by IN delivery using the disclosed epinephrine formulations for various treatments or indications.
Bibliography:Application Number: EP20210800119