QUININE AND ITS USE TO GENERATE INNATE IMMUNE RESPONSE

The invention provides methods and compositions for assaying infectivity of viruses and potential treatments of such viruses in the upper respiratory tract using an air-liquid interface model with nasal epithelium cells; and treatment of viral infections of the upper respiratory tract by treating wi...

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Main Authors Cohen, Noam, Cherry, Sara, Weiss, Susan, R, Adappa, Nithin, D, Tan, Li, Hui, Lee, Robert, J, Maslow, Joel, N, Roberts, Christine, C, Kohanski, Michael, Palmer, James, N
Format Patent
LanguageEnglish
French
German
Published 01.03.2023
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Summary:The invention provides methods and compositions for assaying infectivity of viruses and potential treatments of such viruses in the upper respiratory tract using an air-liquid interface model with nasal epithelium cells; and treatment of viral infections of the upper respiratory tract by treating with bitter taste receptor agonists that stimulate NO production and/or antimicrobial protein production.
Bibliography:Application Number: EP20210793253