HUMAN MACROPHAGES RESISTANT TO TUMOR-INDUCED REPOLARIZATION

The present invention discloses a human macrophage comprising at least one mutation in both alleles of a gene located on a chromosome, wherein the macrophage is resistant to M-CSF induced M2-polarization.

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Bibliographic Details
Main Authors SIEWEKE, Michael, LUI ELENDNER, Clara Jana, FAVRET, Jeremy, QODS, Lahmar, SARRAZIN, Sandrine
Format Patent
LanguageEnglish
French
German
Published 15.02.2023
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Summary:The present invention discloses a human macrophage comprising at least one mutation in both alleles of a gene located on a chromosome, wherein the macrophage is resistant to M-CSF induced M2-polarization.
Bibliography:Application Number: EP20210190989