COMPOSITIONS AND METHODS CONTAINING REDUCED NICOTINAMIDE RIBOSIDE FOR PREVENTION AND TREATMENT OF PANCREATIC DISEASES AND CONDITIONS

• Main Authors: CHRISTEN, Stefan, CANTO ALVAREZ, Carles, JOFFRAUD, Magali, MOCO, Sofia, CERCILLIEUX, Angelique, GINER, Maria, Pilar
• Format: Patent
• Language: English; French; German
• Published: 18.01.2023
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention provides compounds and compositions containing reduced nicotinamide riboside for use in methods of prevention and/or treatment of pancreatic disease and/or conditions. In one embodiment of the invention, said compounds and compositions of the invention maintain or improve pancreatic tissue function. In another embodiment of the invention, compounds and compositions of the invention may be used in methods to prevent and/or treat pancreatic diseases and/or conditions such as: acute or chronic pancreatitis; pancreatitis associated with diabetes mellitus, cystic fibrosis, or exocrine pancreatic insufficiency or hereditary pancreatitis; pancreatic cancer; and/or recovery after pancreatic injury or surgery.