GRANULES CONTAINING POSACONAZOLE

The present invention relates to granules prepared by subjecting a mixture containing posaconazole, an enteric polymer and a non-enteric polymer to hot-melt extrusion, whereby the granules have a specific particle size distribution and contain the drug in molecularly dispersed form, and a gastro-res...

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Bibliographic Details
Main Authors PRATHAP, Vamshi Ramana, FITZNER, Ansgar, ZOUBARI, Gaith, RALLABANDI, Bala Ramesha Chary, VELCHURI, Srikanth, KALAMATA, Venkatasimhadri Naidu, MADALLAPALLI, Kiran Kumar
Format Patent
LanguageEnglish
French
German
Published 23.11.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to granules prepared by subjecting a mixture containing posaconazole, an enteric polymer and a non-enteric polymer to hot-melt extrusion, whereby the granules have a specific particle size distribution and contain the drug in molecularly dispersed form, and a gastro-resistant, optionally film-coated tablet prepared from the granules.
Bibliography:Application Number: EP20220156597