METHODS OF TREATMENT AND/OR PREVENTION OF MAJOR ADVERSE CARDIOVASCULAR EVENTS (MACE) WITH A COMBINATION OF A BET BROMODOMAIN INHIBITOR AND A DIPEPTIDYL PEPTIDASE 4 INHIBITOR

Described herein are methods of for treating and/or preventing Major adverse cardiovascular events (MACE) by administering to a subject in need thereof, a combination of a dipeptidyl peptidase 4 (DPP-4) inhibitor and a compound of Formula I or a stereoisomer, tautomer, pharmaceutically acceptable sa...

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Bibliographic Details
Main Authors KHAN, Aziz, Naeem, LEBIODA, Kenneth, Eugene, HALLIDAY, Christopher, Ross Armstrong
Format Patent
LanguageEnglish
French
German
Published 28.02.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Described herein are methods of for treating and/or preventing Major adverse cardiovascular events (MACE) by administering to a subject in need thereof, a combination of a dipeptidyl peptidase 4 (DPP-4) inhibitor and a compound of Formula I or a stereoisomer, tautomer, pharmaceutically acceptable salt, or hydrate thereof, wherein the variables of Formula I are as defined herein.
Bibliography:Application Number: EP20210738197