METHODS FOR QUANTITATING EXTRA-CELLULAR VESICLE SURFACE MARKERS, AND COMPOSITIONS FOR PRACTICING THE SAME

Methods of quantitating extra-cellular vesicle surface markers are provided. Aspects of the methods include comparing: a mean fluorescence intensity of a surface marker of interest (surface marker MFI) of a labeled extra-cellular vesicle (EV) sample with a calibration plot obtained from a liposome c...

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Bibliographic Details
Main Authors MEHRPOUYAN, Majid, GURYEV, Oleg
Format Patent
LanguageEnglish
French
German
Published 03.05.2023
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:Methods of quantitating extra-cellular vesicle surface markers are provided. Aspects of the methods include comparing: a mean fluorescence intensity of a surface marker of interest (surface marker MFI) of a labeled extra-cellular vesicle (EV) sample with a calibration plot obtained from a liposome calibration composition to quantitate the surface marker on extra-cellular vesicles of the EV sample. Also provided are compositions that find use in practicing embodiments of the invention.
Bibliography:Application Number: EP20200903177