PROCESS FOR THE PREPARATION OF CORTEXOLONE 17 A-PROPIONATE AND NEW HYDRATED CRYSTALLINE FORM THEREOF
The present invention is directed to a process for the preparation of cortexolone 17α-propionate, comprising a hydrolysis reaction of an ortho-ester of formula (III)in which R is a hydrogen atom or a methyl group,in the presence of a dilute solution of acetic acid.The present invention is also direc...
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Main Authors | , , , |
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Format | Patent |
Language | English French German |
Published |
12.10.2022
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention is directed to a process for the preparation of cortexolone 17α-propionate, comprising a hydrolysis reaction of an ortho-ester of formula (III)in which R is a hydrogen atom or a methyl group,in the presence of a dilute solution of acetic acid.The present invention is also directed to a hydrated crystalline form of cortexolone 17a-propionate obtained by such process. |
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Bibliography: | Application Number: EP20220152647 |