DIAGNOSING OF MOOD DISORDERS USING BLOOD RNA EDITING BIOMARKERS

• Main Authors: CHIMIENTI, Fabrice, WEISSMANN, Dinah, SALVETAT, Nicolas
• Format: Patent
• Language: English; French; German
• Published: 14.09.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

The present invention is drawn to a method for in vitro diagnosing mood disorders particularly depression disorders, more preferably major depressive disorder (MDD) in a human patient from a biological sample of said patient, using at least one or a combination of particular A to I editing RNA biomarkers associated to a specific depression score and algorithm. The present invention is also directed to a method for monitoring treatment for mood disorders in a human subject, preferably for monitoring depression and MDD, said method implementing the method for diagnosing mood disorders of the present invention. Kit for determining whether a patient presents a mood disorder, preferably depression disorder, more preferably MDD, is also comprised in the present invention.