NEISSERIA MENINGITIDIS COMPOSITIONS AND METHODS THEREOF

The invention relates to variants of the 2086 lipoprotein from Neisseria meningitidis, also known as factor H binding protein (fHBP) or ORF2086, in particular to an isolated polypeptide comprising the amino acid sequence set forth in SEQ ID NO: 68 and, to immunogenic compositions comprising such pol...

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Bibliographic Details
Main Authors ANDERSON, Annaliesa Sybil, JANSEN, Kathrin Ute, RUPPEN, Mark E, HOISETH, Susan Kay, MORAN, Justin Keith
Format Patent
LanguageEnglish
French
German
Published 17.08.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to variants of the 2086 lipoprotein from Neisseria meningitidis, also known as factor H binding protein (fHBP) or ORF2086, in particular to an isolated polypeptide comprising the amino acid sequence set forth in SEQ ID NO: 68 and, to immunogenic compositions comprising such polypeptide variant, especially non-lipidated, non-pyruvylated forms thereof.
Bibliography:Application Number: EP20220154276