SKIN CARE COMPOSITION COMPRISING MEVALONOLACTONE

Compositions and methods are provided for producing crystalline forms of organic acids or salts or lactones thereof from an aqueous solution. More specifically, methods are provided for producing a crystalline form of a salt of mevalonic acid (also referred to as X-MVA) from an aqueous solution, com...

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Main Authors JENSEN, Henrik Max, GHERARDI, Carole, TIIHONEN, Kirsti, WHITED, Gregory M, MENTUNEN, Tero Tuomas, NURMI, Juha, PERICU, Piera Mattia, JÄRVINEN, Juho, KOIVIKKO, Hannu, KUUSISTO, Jyrki, HUUSKONEN, Laura Tiina Maria, SÄRELÄ, Pertti Matias, SIITONEN, Jani, ANGLENIUS, Heli
Format Patent
LanguageEnglish
French
German
Published 06.07.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Summary:Compositions and methods are provided for producing crystalline forms of organic acids or salts or lactones thereof from an aqueous solution. More specifically, methods are provided for producing a crystalline form of a salt of mevalonic acid (also referred to as X-MVA) from an aqueous solution, comprising subjecting the aqueous solution comprising said X-MVA to a purification step to produce a purified solution and crystallizing said X-MVA from said purified solution by water solvent crystallization. Methods are also provided for producing mevalonolactone from an aqueous solution comprising X-MVA, comprising subjecting the aqueous solution comprising said X-MVA to cation exchange thereby converting said aqueous solution comprising X-MVA to an aqueous solution comprising mevalonolactone (MVL). Methods are also provided for producing mevalonolactone monohydrate crystals.
Bibliography:Application Number: EP20200767914