PROCESS FOR THE PREPARATION OF APALUTAMIDE

Aspect of the present application relates to process for the preparation of crystalline form of Apalutamide and process for the preparation of Apalutamide in the presence of neutralizing agent selected from triethylsilylchloride, trimethylsilyl chloride, zinc chloride, aluminium chloride, iron chlor...

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Main Authors MADAVARAM, Sateesh, IRENI, Babu, REHANI, Rajeev, SUD, Abhishek, ARIGE, Ashok, SEKHAR, Nm, CHADA, Narsihma Reddy
Format Patent
LanguageEnglish
French
German
Published 29.06.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Aspect of the present application relates to process for the preparation of crystalline form of Apalutamide and process for the preparation of Apalutamide in the presence of neutralizing agent selected from triethylsilylchloride, trimethylsilyl chloride, zinc chloride, aluminium chloride, iron chloride, sodium chloride, acetic acid, ammonium chloride or mixture thereof followed by treating with acid to obtain Apalutamide.
Bibliography:Application Number: EP20200855238