ACTIVE-TARGETING NEAR-INFRARED FLUORESCENT MOLECULE FOR TARGETING FOLATE RECEPTOR AND PREPARATION METHOD THEREFOR

The present disclosure relates to the fields of near-infrared surgical navigation fluorescent molecules, cell marker imaging and so on, and in particular discloses an active targeting near-infrared fluorescent small molecule structure and a preparation method thereof. The present disclosure prepares...

Full description

Saved in:
Bibliographic Details
Main Authors WANG, Yiqing, CAI, Huiming
Format Patent
LanguageEnglish
French
German
Published 24.08.2022
Subjects
ADHESIVES
CHEMISTRY
DYES
HETEROCYCLIC COMPOUNDS
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE
MEASURING
METALLURGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
NATURAL RESINS
ORGANIC CHEMISTRY
PAINTS
PHYSICS
POLISHES
TESTING
Online AccessGet full text

Cover

More Information
Summary:The present disclosure relates to the fields of near-infrared surgical navigation fluorescent molecules, cell marker imaging and so on, and in particular discloses an active targeting near-infrared fluorescent small molecule structure and a preparation method thereof. The present disclosure prepares the active targeting near-infrared fluorescent small molecule with pemetrexed disodium and derivatives thereof as active targeting groups by utilizing an organic total synthesis method. Such active targeting near-infrared fluorescent molecule has the advantages of high active targeting property, strong specificity, good water solubility, high fluorescence quantum yield and so on.
Bibliography:Application Number: EP20200929674