HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS

Provided are compounds of Formula (I) and pharmaceutical acceptable salts thereof, which are inhibitors of WDR5. Also providing pharmaceutical compositions comprising such compounds, compositions comprising such compounds with an additional therapeutic agent and the therapeutic uses of such compound...

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Bibliographic Details
Main Authors XIAO, Qitao, GAO, Zhenting, LIU, Kevin Kun Chin, WU, Jianping, FANG, Lichao, JIANG, Xiangqing, YINGMING, Wu, MAK, Sing Yeung Frankie, WANG, Ce, OYANG, Counde, WANG, Tao
Format Patent
LanguageEnglish
French
German
Published 15.06.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided are compounds of Formula (I) and pharmaceutical acceptable salts thereof, which are inhibitors of WDR5. Also providing pharmaceutical compositions comprising such compounds, compositions comprising such compounds with an additional therapeutic agent and the therapeutic uses of such compounds.
Bibliography:Application Number: EP20200754394