PYRAZOLONE AND PYRIMIDINE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR

Disclosed in the present invention are a pyrazolone and pyrimidine compound, and a preparation method and a use therefor. Provided in the present invention is a pyrazolone and pyrimidine compound as in formula (I), said compound having better inhibitory activity towards WEE1 kinase.

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Bibliographic Details
Main Authors YU, Jianxin, GE, Hui, ZHANG, Zhihui, XIA, Guangxin, SHU, Sijie, ZHANG, Bingbin, SHI, Chen, KE, Ying, LIU, Yanjun, LOU, Jiangsong, HUO, Guoyong, WANG, Qian, MAO, Yu, ZHANG, Chi, ZHANG, Lin
Format Patent
LanguageEnglish
French
German
Published 08.06.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed in the present invention are a pyrazolone and pyrimidine compound, and a preparation method and a use therefor. Provided in the present invention is a pyrazolone and pyrimidine compound as in formula (I), said compound having better inhibitory activity towards WEE1 kinase.
Bibliography:Application Number: EP20200831960