STRAIN AND METHOD FOR PRODUCING ROSMARINIC ACID

Provided are a strain and method for producing rosmarinic acid. Recombinant cells expressing 4-coumarate-CoA ligase, rosmarinic acid synthase, polyphosphate kinase 2-1 and polyphosphate kinase 2-II or combinations of the recombinant cells are constructed, and the recombinant cells or the combination...

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Bibliographic Details
Main Authors YAN, Yi, BAI, Yajun, DING, Yanrui, CAI, Yujie, ZHENG, Xiaohui
Format Patent
LanguageEnglish
French
German
Published 04.05.2022
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Provided are a strain and method for producing rosmarinic acid. Recombinant cells expressing 4-coumarate-CoA ligase, rosmarinic acid synthase, polyphosphate kinase 2-1 and polyphosphate kinase 2-II or combinations of the recombinant cells are constructed, and the recombinant cells or the combinations of the recombinant cells are used for catalyzing synthesis of rosmarinic acid from Danshensu and caffeic acid.
Bibliography:Application Number: EP20200830994