CHIMERIC ANTIGEN RECEPTORS CONTAINING A CHLOROTOXIN DOMAIN

Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular...

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Bibliographic Details
Main Authors FORMAN, Stephen J, WANG, Dongrui, BARISH, Michael, BROWN, Christine E
Format Patent
LanguageEnglish
French
German
Published 20.04.2022
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Summary:Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.
Bibliography:Application Number: EP20210197997