HOMOGENEOUS IMMUNOASSAY METHOD USING PEPTIDE HAVING MULTIPLE FLUOROCHROMES JOINED THERETO

As a simple antigen detection approach using Q-body, provided is a kit for antigen detection, comprising: a first peptide conjugated with two fluorescent dyes capable of forming a FRET pair or a fluorescent dye and a luminescent material capable of forming a BRET pair, and an antibody fragment with...

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Bibliographic Details
Main Authors OHMURO, Yuki, INOUE, Akihito, UEDA, Hiroshi, YASUDA, Takanobu, KITAGUCHI, Tetsuya
Format Patent
LanguageEnglish
French
German
Published 13.04.2022
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:As a simple antigen detection approach using Q-body, provided is a kit for antigen detection, comprising: a first peptide conjugated with two fluorescent dyes capable of forming a FRET pair or a fluorescent dye and a luminescent material capable of forming a BRET pair, and an antibody fragment with a second peptide added thereto, wherein 1) one of the first peptide and the second peptide is positively charged, and the other peptide is negatively charged, and 2) the first peptide and the second peptide are capable of forming a coiled coil.
Bibliography:Application Number: EP20200817957