PHARMACEUTICAL COMPOSITION COMPRISING A PI3K DELTA SELECTIVE INHIBITOR FOR USE IN THE TREATMENT OF PI3K MEDIATED DISEASES

The divisional application relates to a pharmaceutical composition comprising a p-toluenesulfonic acid salt (PTSA) of the selective PI3K delta inhibitor (S)-2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one (TGR-1202) a...

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Bibliographic Details
Main Author Vakkalanka, Swaroop Kumar Venkata Satya
Format Patent
LanguageEnglish
French
German
Published 23.03.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The divisional application relates to a pharmaceutical composition comprising a p-toluenesulfonic acid salt (PTSA) of the selective PI3K delta inhibitor (S)-2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one (TGR-1202) and a solubilizer, and to the pharmaceutical composition for use in the treatment of a PI3K kinase mediated disease or disorder such as cancer.
Bibliography:Application Number: EP20210182208