DETECTION OF MALIGNANT TUMOR CELLS ANTIBODIES AND USES THEREOF

Disclosed are an anti-ROR2 antibody and a use thereof. The anti-ROR2 antibody includes: a light chain variable region with amino acid sequence of CSASSSVSYMHWYQ, IYDTSKLAS and CQQWSSNPPTFGAG, and a heavy chain variable region with amino acid sequence of YTITSYLMHWV, LEWIGYINPYNDGTKYNEKFKDKAT and CAR...

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Bibliographic Details
Main Authors KIPPS, Thomas James, WU, Liufeng, ZHANG, Suping
Format Patent
LanguageEnglish
French
German
Published 07.09.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are an anti-ROR2 antibody and a use thereof. The anti-ROR2 antibody includes: a light chain variable region with amino acid sequence of CSASSSVSYMHWYQ, IYDTSKLAS and CQQWSSNPPTFGAG, and a heavy chain variable region with amino acid sequence of YTITSYLMHWV, LEWIGYINPYNDGTKYNEKFKDKAT and CARSDVYYGVRFAYWGQG; a light chain variable region with amino acid sequence of CKASQNVGTNVAWFQ, IYLASYRYS and CQQYNSYPLTFGGG, and a heavy chain variable region with amino acid sequence of YTFTNYWIQWM, LEWIGEINPSNGRTDYNEKFKNRAT and CANYRPGYWGQG; and a light chain variable region with amino acid sequence of CSASSSISYMYWYQ, IYDTSILAS and CQQWSSYPFTFGSG, and a heavy chain variable region with amino acid sequence of YTFTSYLIHWV, LEWIGYINPYNDGTKYNEKFKDKAT and CARSDVYYGVRFAYWGQG.
Bibliography:Application Number: EP20190909467