PERAMIVIR SOLUTION TYPE INHALANT AND PREPARATION METHOD THEREFOR

A peramivir solution inhalant and a preparation method thereof are provided, the solution inhalant includes: peramivir, an osmotic pressure regulator, a pH regulator, and water, wherein concentration of peramivir is greater than 15 mg/ml; concentration of the osmotic pressure regulator is less than...

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Bibliographic Details
Main Authors FENG, Yuhuan, MIAO, Dong, ZHANG, Shixi
Format Patent
LanguageEnglish
French
German
Published 05.01.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A peramivir solution inhalant and a preparation method thereof are provided, the solution inhalant includes: peramivir, an osmotic pressure regulator, a pH regulator, and water, wherein concentration of peramivir is greater than 15 mg/ml; concentration of the osmotic pressure regulator is less than 8 mg/ml; pH value of the solution inhalant ranges from 5.0 to 6.0; the peramivir solution is sterilized in a non-heating manner; the osmotic pressure regulator is selected from sodium chloride or glucose. The solution inhalant has a better stability and a good pulmonary targeting effect, which significantly improves pharmaceutical efficacy and safety.
Bibliography:Application Number: EP20190917241