LIPID PRODRUGS OF JAK INHIBITORS AND USES THEREOF

The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The pr...

Full description

Saved in:
Bibliographic Details
Main Authors BONNER, Daniel Kenneth, HAN, Sifei, QUACH, Tim, MCINERNEY, Mitchell, SIMPSON, Jamie, KARANAM, Ketki, TREVASKIS, Natalie, SHARMA, Garima, LEONG, Nathania, BOLEN, Joseph, ZHENG, Dan, PORTER, Christopher John
Format Patent
LanguageEnglish
French
German
Published 09.11.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.
Bibliography:Application Number: EP20200762421