SUPPLEMENTED SERUM-CONTAINING CULTURE MEDIUM FOR ENHANCED ARPE-19 GROWTH AND HUMAN CYTOMEGALOVIRUS VACCINE PRODUCTION
The present invention relates to supplemented serum-containing cell culture media that provides enhances ARPE-19 cell growth and/or improves the yield of human cytomegalovirus (HCMV) grown in ARPE-19 cell cultures. The media of the invention includes two additives, a hormone (e.g., a glucocorticoid...
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Main Authors | , , , |
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Format | Patent |
Language | English French German |
Published |
05.10.2022
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to supplemented serum-containing cell culture media that provides enhances ARPE-19 cell growth and/or improves the yield of human cytomegalovirus (HCMV) grown in ARPE-19 cell cultures. The media of the invention includes two additives, a hormone (e.g., a glucocorticoid hormone such as dexamethasone) and a growth factor (e.g., EGF). The invention further provides methods of producing HCMV in such growth media. |
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Bibliography: | Application Number: EP20190907032 |