OPTICAL SYSTEM, METHOD FOR CALIBRATING OPTICAL SYSTEM, AND SEQUENCING SYSTEM

• Main Authors: QI, Jifang, JIANG, Zefei, ZHOU, Zhiliang, YAN, Qin
• Format: Patent
• Language: English; French; German
• Published: 19.01.2022
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS; OPTICS; PHYSICS; TESTING

An optical system, a method for calibrating the optical system, and a sequencing system, the optical system comprising a first light source (12), a first lens (16), a first optical splitter (14), a second lens (18), a first camera (20), and a second camera (22), the first lens (16) being used for receiving a first light beam from the first light source (12) and collimating the first light beam to be incident on a sample (24), and being used for receiving a light beam from the sample (24) and collimating the light beam, the second lens (18) being used for focusing the collimated light beam from the first lens (16) onto the first camera (20) and the second camera (22), the first optical splitter (14) being used for splitting the focused light beam from the second lens (18) into a second light beam and a third light beam, the first camera (20) being used for receiving the second light beam, and the second camera (22) being used for receiving the third light beam. The optical system is based on a split optical path design, and comprises the light beam being split after passing through the second lens, enabling the total length of the optical path of the optical system to be shortened and the required space reduced, being conducive to miniaturisation of the optical system.